Сабақ №1. Органикалық қосылыстардың құрылымдық негізі мен реакциялық қабілеттілігі
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МЕТОДИЧКА ДЛЯ СТУДЕНТОВ.ТФП. КАЗ.ОХ 2023-2024 гг..doc
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кеңес беру кезеңінде кері байланыс түрінде . СӨЖ арналған тапсырма: Spatial structure of organic compounds (тапсырманы ағылшын тілінде орындаймыз). 1. Optical isomerism. Asymmetric carbon atom. Optical activity. The configuration standard is glycerin aldehyde. Stereoisomers with one and several centers of chirality. D and L rows. Enantiomers. Diastereomers. Racemate. 2. Amino alcohols: ethanolamine, choline, acetylcholine, their biological significance as neurotransmitters. 3. Aminophenols. Dopamine, norepinephrine, adrenaline are biogenic amines, their biological significance as hormones. 4. Hydroxyacids: glycolic, lactic, malic, tartaric and citric acids. 5. Aldehyde and keto acids (oxo acids): glyoxylic, pyruvic, acetoacetic, oxaloacetic, α-ketoglutaric acid. Keto-enol tautomerism on the example of acetoacetic ester. 6. Phenolic acids: salicylic, acetylsalicylic, para-aminosalicylic acid - as medicines. 7. Write the reactions: 1) oxidation of lactic acid with NAD + ; 2) recovery of oxaloacetic acid with NADH 2 . What are the reaction products obtained?. 8. Which of carboxylic groups of 2-oxopentanedioic (α-ketoglutaric) acid could be easier «С.Ж. АСФЕНД ИЯРОВ АТЫНД АҒЫ ҚАЗАҚ ҰЛТТЫҚ МЕД ИЦИНА УНИВЕРСИТЕТІ» КЕАҚ НАО «КАЗАХСКИЙ НАЦИОНАЛЬНЫЙ МЕД ИЦИНСКИЙ УНИВЕРСИТЕТ ИМЕНИ С.Д .АСФЕНД ИЯРОВА» Кафедра химии Методичка Редакция: 1 Страница 21 из 37 decarboxylated and why? Write this reaction and name the reaction product. 9. Write the keto-enol tautomerism equilibrium of ethyl acetoacetic acid (3-oxobutanoic acid). Which of the tautomeric forms of acetoacetic acid could react with bromine water? Write the reaction. 10. Write aldol condensation reaction of oxaloacetic (oxobutanedioic) acid with acetyl coenzyme A. 11. Write the reactions of salicylic acid derivatives formation: (a) methyl salicylate; (b) sodium salicylate; (c) phenyl salicylate; (d) acetylsalicylic acid. What reagents should be used for these reactions? жүктеу/скачать 1,37 Mb. Достарыңызбен бөлісу:
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