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occurring in the liver causes its high sensitivity to a lack of oxygen. An activation of lipid
peroxidation in the liver plays an important role in metabolic disorders in acute hypoxia.
Futhermore, the relationship between the indicators of fetal hemoglobin and oxygen
saturation in
patients with hemoglobinopathies including sickle cell anemia helps in the
early diagnosis of latent chronic hypoxia and hypoxemia, allowing to clarify the severity of
the disease and correct treatment.
Finally, the antioxidant activity of flavonoids is
manifested in an increase in the antioxidant status of plasma including a protective effect
of vitamin E. Its action is directed on erythrocyte membranes and low density lipoproteins,
as well as the protection of PUFA membranes of red blood cells from peroxidation.
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