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SEASONAL DYNAMICS OF HEMATOLOGICAL INDEXES OF THE BLOOD OF ANIMALS IN
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| SEASONAL DYNAMICS OF HEMATOLOGICAL INDEXES OF THE BLOOD OF ANIMALS IN
A NORM AND AT THE INFLUENCE OF HEAVY METALS Matayeva K.S., Turyskeldi Sh.S., Ablaikhanova N.T. al-Farabi Kazakh National University kary.95@mail.ru Blood as one of the most important systems of an organism, plays an important role in its activity. Being in close contact with fabrics, blood has all jet properties of fabrics, but its sensitivity to pathological irritations is higher and thinner, and the reactivity – is more expressive and more impressive. Therefore any impacts on body tissues affect structure and properties of blood. Therefore the hematological analysis as one of methods of clinical diagnostics, found broad application in biology and medicine. Various researches of system of blood conducted during all annual cycle demonstrate that the composition of peripheral blood undergoes the considerable seasonal changes. During the spring and summer period inverse is often observed natural dynamics of a hemopoiesis, and indexes of blood are characterized by the larger range of variation. For example, fluctuations of level of leukocytes are not essential and do not overstep the bounds of physiological norm. Only small increase in frequency of occurrence of pseudoeosinophils and eosinocytes during the spring and autumn periods is usually observed. In the fall the most high level of erythrocytes in blood of animals is established. Minimum concentration of a hemoglobin and erythrocytes are noted during the summer period. By fall and winter indicators of red blood increase, concentration of leukocytes - decreases. Level of a concentrate of serumal protein, a blood sedimentation rate, the common protein of serum, percent of neutrophils, eosinocytes from summer by winter decrease, and the share of monocytes significantly increases. To spring warming there is on the way of reliable weakening of a hemoglobin, increase in a blood sedimentation rate, the relation Er:l, activization eritro-and a granulopoiesis. The biomarkers demonstrating toxic impact on an organism of animals and essential deterioration in an ecological condition of the environment are concentration of a hemoglobin, erythrocytes, leukocytes, average content of a hemoglobin in one erythrocyte, a color index of blood, percentage of neutrophilic myelocytes, neutrophilic metamyelocytes, stabnoid and segmented neutrophils, monocytes; major axis of erythrocytes, perimeter, area, erythrocyte ellipse shape factor; agglutination of erythrocytes, hemolysis, microcytic anemia, hypochromia, poikilocytosis, vacuolization of erythrocyte cytoplasm, leaching of erythrocyte nuclei, displacement of erythrocyte nuclei to the periphery of the cell. Reaction of system of blood of animals to influence of ions of copper, lead, cadmium and hydrargyrum is shown, first of all, in increase in perimeter, the area, small and big axes of erythrocytes, decrease of percent small and increase in percent of larger lymphocytes and also change of a leukocytic formula, morphology of erythrocytes and depends on a type of metal, its concentration in water, duration of impact on an organism of animals. Less sensing indicators to influence of ions of heavy metals are concentration of Hb, Er and especially average content of a hemoglobin in one erythrocyte. Thus, blood, being the internal environment of an organism, quickly and precisely reacts to changes of a surrounding medium, always and unmistakably reflects a physiological condition of an organism, demonstrating character and weight of an aberration. Fluctuations of indexes are bound to seasonal changes and physiological adaptation of an organism and also to toxic influence. Supervisor: Candidate of Biological Sciences, Associate Professor, Ablaikhanova N.T. жүктеу/скачать 2,79 Mb. Достарыңызбен бөлісу:
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