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ABNORMAL CHANGES IN THE ORGANS OF RATS UNDER THE ACTION OF TOXIC
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| ABNORMAL CHANGES IN THE ORGANS OF RATS UNDER THE ACTION OF TOXIC
SUBSTANCES Yeltay G., Mukash A. al-Farabi Kazakh National University, Almaty, Kazakhstan gulmira280595@mail.ru One of the main reasons for the environmental influence on the human body is the impact of a huge amount of toxic substances. Toxins affect people through inhaled air, consumed food and water, and through the skin. Under the influence of toxic substances in the organs, pathological processes occur, accompanied by morphological changes in the tissues. An experiment was performed on 30 white outbred rats - males of three months of age with an initial mass of 180-200 grams. The histological treatment of the material was carried out by the traditional method of microscopic technique of preparation of thin sections (Volkova and Yeletsky, 1982). The results of histologic examination of the intestine and stomach in the control rats of the first group on semitinous sections showed that all organs were normal, when exposed to crude oil showed pronounced changes in the destructive nature in the small intestine and minor morphological changes in the 77 compensatory-adaptive nature in the colon. As a result of the histologic examination of the organs of the experimental rats of the third group after poisoning with crude oil through using enterosorbent, it can be seen that morphological studies of the action of enterosorbent on the stomach of rats showed no strong pathomorphological changes in the structure of this organ.When entering the intestinal lumen of the oil, the secretion of mucus by goblet cells increased. Feeding rats with crude oil leads to severe destructive disorders of the intestine and stomach organs, and the application of enterosorbent contributed to a reduction in dystrophic processes and an increase in compensatory-adaptive reactions. жүктеу/скачать 2,79 Mb. Достарыңызбен бөлісу:
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