METHODOLOGICAL INSTRUCTIONS FOR PRACTICAL LESSONS
discipline "From molecule to cell"
Practical lesson 1:
Atoms. Subatomic particles: electrons, protons, neutrons. Atomic properties: mass, charge. Chemical elements: periodic table, isotopes, ions. Radioactivity: alpha, beta, gamma radiation.
describe the structure of atoms in terms of protons, neutrons and electrons
know what is meant by a chemical element and how they are located in the periodic table
understand the valency, atomic number and atomic mass of chemical elements
define the terms: isotopes, isotope stability, radioactivity, radioactive radiation to present the general principles of nuclear chemistry
describe alpha, beta, positron and gamma radiation and be able to write a balanced nuclear equation for radioactive decay with mass numbers and atomic numbers
Molecules. Interaction between atoms: covalent bonds, non-covalent interactions. Inorganic compounds: acids, bases, salts, oxides. Electronegativity; chemical polarity and dipole moment.
distinguish between molecular and non-molecular substances
identify inorganic compounds: base, acid, oxide, salt. List their distinguishing features
get familiar with organic compounds
classify intermolecular and intramolecular forces
understand how the concept of electronegativity and its variations in the periodic table can be used to explain the nature of bonding in substances
Practical lesson 2:
Types of chemical reactions and stoichiometry
understand what chemical reaction is
state 3 principles of collision theory for interpreting interactions between molecules
identify chemical reactions as reactions of combination, decomposition, substitution or combustion
determine the reaction rate and factors affecting the reaction rate
construct balanced chemical equations to represent reactions
Stereochemistry and chirality
Enantiomers and chirality. Asymmetric carbon and stereocenters. Chirality and symmetry. Nomenclature R,S. Optical activity, diastereoisomers and mesocompounds. enantiomeric resolution. The importance of asymmetry.
classify stereoisomers
draw the cis-trans isomers resulting from restricted rotation. Determine chiral carbon; differentiate between chiral and achiral molecules
determine the stereocenters in the molecule and assign the configuration as R or S using the Cahn-Ingold-Prelog protocol
list the requirements for molecules in terms of their optical activity
explain the relationship between enantiomers and their specific rotations
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