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"SCIENCE AND EDUCATION IN THE MODERN WORLD



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"SCIENCE AND EDUCATION IN THE MODERN WORLD:
CHALLENGES OF THE XXI CENTURY" 
NUR-SULTAN, KAZAKHSTAN, JULY 2019
 
353 
 
UDC 615.32:582.734 
 
CHEMICAL CONSTITUENTS OF THE AGRIMONIA ASIATICA EXTRACTS 
 
Kozykeyeva Raushan
PhD student at JSC NMU, Almaty, Kazakhstan 
Scientific consultants - Datkhayev Ubaidilla, Patsayev Anapiya
ABSTRACT 
Agrimonia asiatica is one of the valuable plant source of drugs in traditional medicine 
used from an ancient time in China, Japan due to containing of many biologically active 
compounds. Agrimonia genus bioactive compounds exhibit antiviral, antibacterial, anti-
inflammatory, anti-carcinogenic, and antioxidant activity. By this way, we have selected aerial 
part of A.asiatica to study their phytoconstituents. For the phytochemial analysis dried 
powdered aerial part of A.asiatica was extracted with organic solvents: chloroform, ethanol 
(96%). Prepared extracts were used to carry out qualitative phytochemical analyses by using 
GC-MS method. 
Keywords: Agrimonia asiatica, GC-MS, phytochemicals, bioactive compounds, 
neophytodiene. 
Introduction. The plant A.asiatica belongs to the family Rosaceae, which comprises 
over 300 plant species occurring worldwide. In Kazakhstan, A.asiatica is a native plant growing 
commonly in meadow, scrub, and ruderal communities across lowland areas and lower montane 
zones, along forest margins and on slopes. The species is a widespread plant. The plant blooms 
in July and August. Herba agrimoniae herb is the therapeutic material from A.eupatoria L. It is 
a source of many bioactive compounds, primarily terpenes, phenolic compounds, tannins, 
flavonoids, proteins, carbohydrates, and vitamins [1]. Agrimonia eupatoria L. from the 
Rosaceae family has emerged as a potential source of phenolic constituents, showing 
antioxidant activities [2]. In previous studies from dried aerial parts of Agrimonia pilosa a 
homogenous polysaccharide (APP) was isolated and Gas chromatography (GC) and GC-MS 
analysis revealed that APP has a backbone of 1,3-linked Glcp and 1,3, 6-linked Glcp, and 
branched with 1-linked Glcp terminal along the main chain in a relative ratio of 2:1:1. Scientists 
investigated the response of human osteosarcoma U-2 OS cells to APP treatment [3]. As the 
aerial parts of the plants genus Agrimoni have many pharmacological activity, hence the 
present investigation to evaluate that phytoconstituent of aerial parts of the plant with the help 
of GC-MS, which will help for further pharmacological evaluation. Several phytoconstituents 
analyses have been carried out in many parts of the world by GC-MS technique [4].The aim of 
this study is to identify qualitative volatile compounds of the A.asiatica extracts 


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