Белок функциясы Alberts Β (1998) The cell as a collection of
protein machines: preparing the next genera-
tion of molecular biologists. Cell 92, 291-294.
Benkovic SJ (1992) Catalytic antibodies.
Annu. Rev. Biochem. 61, 29-54.
Berg OG & von Hippel PH (1985) Diffu-
sion-controlled macromolecular interactions.
Annu. Rev. Biophys. Biophys. Chem. 14, 131-
160.
Bourne HR (1995) GTPases: a family of
molecular switches and clocks. Philos. Trans. R. Soc. Lond. Β Biol. Sci.349, 283-289.
Costanzo M, Baryshnikova A, Bellay J et al.
(2010) The genetic landscape of a cell. Science 327, 425-431.
Deshaies RJ & Joazeiro CAP (2009) RING
domain E3 ubiquitin ligases. Annu. Rev. Bio- chem. 78, 399-434.
Dickerson RE & Geis I (1983) Hemoglobin:
Structure, Function, Evolution, and Pathology.
Menlo Park, CA: Benjamin Cummings.
Fersht AR (1999) Structure and Mechanism
in Protein Science: A Guideto Enzyme Catalysis
and Protein Folding. New York: WH Freeman.
Haucke V, Neher Ε & Sigrist SJ (2011) Pro-
tein scaffolds in the coupling of synaptic exo-
cytosis and endocytosis. Nat. Rev. Neurosci.12,
127-138.
Hua Ζ & Vierstra RD (2011) The cullin-RING
ubiquitin-protein ligases. Annu. Rev. Plant Biol . 62, 299-334.
Hunter Τ (2012) Why nature chose phos-
phate to modify proteins. Philos. Trans. R. Soc. Lond. Β Biol. Sci. 367, 2513-2516.
Johnson LN & Lewis RJ (2001) Structural
basis for control by phosphorylation. Chem. Rev. 101, 2209-2242.
Kantrowitz ER & Lipscomb WN (1988) Esch- erichia colі aspartate transcarbamylase: the re-
lation between structure and function. Science 241, 669-674.
Kerscher O, Felberbaum R & Hochstrasser
Μ (2006) Modification of proteins by ubiquitin
and ubiquitin-like proteins. Annu. Rev. CellDev. Biol. 22, 159-180.
Kim Ε & Sheng Μ (2004) PDZ domain pro-
teins of synapses. Nat. Rev.Neurosci. 5, 771-
781.
Koshland DE Jr (1984) Control of enzyme
activity and metabolic pathways. Trends Bio- chem. Sci. 9, 155-159.
Krogan NJ, Cagney G, Yu Η et al. (2006)
Global landscape of protein complexes in the
yeast Saccharomyces cerevisiae. Nature 440,
637-643.
Lichtarge O, Bourne HR & Cohen FE (1996)
An evolutionary tracemethod defines binding
surfaces common to protein families. J. Mol. Biol. 257, 342-358.
Maier T, Leibundgut Μ & Ban Ν (2008) The
crystal structure of a mammalian fatty acid
synthase. Science321, 1315-1322.
Monod J, Changeux JP & Jacob F (1963)
Allosteric proteins andcellular control systems.
J. Mol. Biol. 6, 306-329.
Perutz Μ (1990) Mechanisms of Cooper-
ativity and Allosteric Regulationin Proteins.
Cambridge: Cambridge University Press.
Radzicka A & Wolfenden R (1995) A profi-
cient enzyme. Science 267, 90-93.
Schramm VL (2011) Enzymatic transition
states, transition-state analogs, dynamics,
thermodynamics, and lifetimes. Annu. Rev. Biochem. 80, 703-732.
Scott JD & Pawson Τ (2009) Cell signaling in
space and time: whereproteins come together
and when they’re apart. Science 326, 1220-
1224.
Taylor SS, Keshwani MM, Steichen JM &
Kornev AP (2012) Evolution of the eukaryotic
protein kinases as dynamic molecular switches.
Philos. Trans. R. Soc. Lond. Β Biol. Sci.367, 2517-
2528.
Vale RD & Milligan RA (2000) The way things
move: looking under the hood of molecular
motor proteins. Science 288, 88-95.
Wilson MZ & Gitai Ζ (2013) Beyond the
cytoskeleton: mesoscale assemblies and their
function in spatial organization. Curr. Opin. Microbiol. 16, 177-183.