Литература
1. Досмагамбетова Р. С. КГМИ. Дело, которому они служили (далёкие и близкие пятидесятые) /Р. С. Досмагам-
бетова, Н. Ф. Сайфулина. – М.: Литтерра, 2015. – С. 20-38.
2. Досмагамбетова Р. С. Пусть им улыбнутся небеса... /Р. С. Досмагамбетова, Н. Ф. Сайфулина. – Караганда,
2015. – С. 160-166.
3. Карагандинский государственный медицинский университет / Под общ. ред. М. К. Телеуова.– Караганда,
2010.– С.14-15.
4. Кулмагамбетов И. Р. Карагандинская государственная медицинская академия: страницы истории / И. Р. Кул-
магамбетов, К. А. Алиханова. – Караганда, 2005.– С.6-16.
5. Поспелов П. М. Производственный травматизм на шахтах Карагандинского угольного бассейна и его анализ
за 1941 – 1950 гг : Автореф. дис. ... канд. мед. наук.– Караганда, 1952.– 11 с.
6. Поспелов П. М. Карагандинский государственный медицинский институт /П. М. Поспелов,
В. А. Брейдо.– Алма-Ата: Казахстан, 1973.– С. 5-8.
7. Сайфулина Н. Ф. Пётр Моисеевич Поспелов – основатель КГМА /Н. Ф. Сайфулина, Е. И. Чуйкина
// Актуальные проблемы организации здравоохранения, клинической и экспериментальной медицины:
Материалы междунар. науч.-практич. конф., посвященной 100-летию со дня рождения П. М. Поспелова, 7-8
ноября 2003г. - Караганда, 2003.– С.27–28.
8. Сейсембеков Т. З. Поспелов Пётр Моисеевич: страницы истории /Т. З. Сейсембеков.– Караганда, 2010.–
С.8-17.
R. S. Dosmagambetova, N. F. Saifulina
CONTRIBUTION OF DOCTOR PYOTR MOISEEVICH POSPELOV IN THE ORGANIZATION, FORMATION AND
DEVELOPMENT OF THE KARAGANDA STATE MEDICAL INSTITUTE
Karaganda State Medical University
The article is devoted to the life and professional activity of Petre Moisseevich Pospelov, who made a greate contribution in
the development of healthcare of Kazakhstan. After graduating from the State Medical Institute in Kuban, P. M. Pospelov worked in
Karaganda, Kazakhstan and devoted 52 years of his live to this city. The authors made a special emphasis of his contribution in the
organization and development of Karaganda State Medical Institute, the second higher medical institution in Kazakhstan. Being the
first Principal of KSMI, P. M. Pospelov played an important role in the preparation of Kazakhstani doctors, whis is highly appreciated
by the Kazakhstani people.
Keywords: institute, students, doctors
UTC 616.24-002/155.194-053.2
A. S. Akhayeva, A. T. Bektursinova , I. A. Skosarev
ANALYSIS OF LEVEL OF BIOMARKERS INFLAMMATION AT COMMUNITY - ACQUIRED
PNEUMONIA IN CHILDREN
Karaganda state medical university, Karaganda
Diseases related to breathing organs in children from the data of WHO during many years occupies a leading
place in the structure of morbidity and death rate in many countries of the world. It is an actual problem in Kazakh-
stan. Annually, about 155 million cases in children suffering from pneumonia is registered in the world. Pneumonial
death rate is approximately 1,8 million in children under the age of five years, that makes 20% of all cases of child’s
death rate [1]. Among the hospitalized children with bronchopulmonary diseases per year is about 25-35% cases of
acute pneumonia.
Organism of child at pathological phase presently is examined as difficult, multicomponent system, functional-
ly during the concerted work of separate links. During immuno-inflammation reactions, produced by monocytic-mac-
rophage polypeptide, getting the name TFN, executes the role of not only effectory neurohumor of cytotoxicity but
also produce death of malignant cells-targets by taking part in adjusting of different physiological and pathological
processes in an organism [2]. In this connection, study of biological activity of TFN and especially mechanisms re-
alizing the working of testimonies and methodologies of clinical application of cytotoxic polypeptide, not only in the
Специальный выпуск журнала «Медицина и экология», 2015
7
МЕДИЦИНСКОЕ ОБРАЗОВАНИЕ — НОВЫЕ ГОРИЗОНТЫ
treatment of patients with malignant tumors but also in other areas of clinical medicine, and also for the searches of
new medicinal facilities regulating in an organism.
Ideas about the role of cytokine, low-molecular albumin cellular mediators participating in realization of in-
tercellular cooperation and adjusting of separate links of metabolism, undoubtedly can bring in understanding the
development of mechanisms of pathological process in pneumonia.
Last year, interest of researchers was drawn towards cytokine, being bioactive connector influence the origin
of inflammatory reaction and processes and cellular proliferation, carrying out an endogenous immuno-regulation.
These connections participate in the processes of fibrinogenesis and determine changes in pulmonary fabric. In
this connection the aim of study is analysis of level of tumor factor of necrosis for children at community acquired
pneumonia.
On analysis, the study of level of indexes of factor of necrosis in tumor was conducted in 36 children having
girls 63% with 5-18 of age. Serum of blood and urine was conducted. The obtained data was treated through the
statistical programs of analysis of data through clinical medicine.
The analysis of the obtained data showed that at comparison of values in children with community acquired
pneumonia depended on age, mostly expressed increase of level of TFN was determined in the children of junior
age group (5-7) years. The obtained data for children with community acquired pneumonia depending on age of
children differed from these indexes in the children of control group (0,01).The same tendencies came to light at
comparison of values for children of age 7-11 (0,01) and group of children of age 11-18. Tendencies, described
higher determined both in the serum of blood 1,5 time and in urine 6 times when compared to indexes for children
in a control group.
At comparison of values TFN for children with community - acquired pneumonia, depending on weight of
process showed that level of TFN in children with heavy pneumonia practically in 2 times exceeded the values in the
children of control group, at the same time for certain, differed from values for children with the middling-heavy
degree of pathological process. The indexes of TFN in urine determined the same tendencies, but a degree of distinc-
tions was more expressed, and values in children with a heavy degree exceeded values for the children of control
group more than in 10 times.
The analysis of indexes TFN in children depending on the form of pneumonia showed presence of the same
tendencies, that at the analysis of indexes depending on weight of process, confirmed dependence of weight of
process in turn from the degree of involving of pulmonary fabric in a pathological process at community acquired
pneumonias. Reliable differences were determined when compared to indexes for the children of control group and
indexes to the different forms of community acquired pneumonia (0,01).
Study of indexes TFN for the inspected children, depending on the presence of anaemic syndrome showed
that for children with an anaemic syndrome, both in the serum of blood and in urine showed reliable differences from
values came to light at comparison for sick children with indexes for children of control group. Differences were made
and compared with groups of children at that pneumonia flowed without an anaemic syndrome.
Consequently, the substantial increase of concentration factor of necrosis of tumor induced depends on ex-
pression of activity of inflammatory process, and with more considerable values in urine.
The obtained data in the serum of blood and urine of children with community acquired pneumonia shows
that they play an important role in the mechanisms of pathogenesis of pneumonias in children and examine the
values of necrosis factor of tumor in the serum of blood and urine, as a laboratory marker of degree of activity of
inflammatory process, and accordingly use determination of tactics of curative events for community- acquired pneu-
monias in children.
Reference:
1. Мухтарова Р.К. Острые пневмонии у детей: классификация, клинические особенности и диагностические
критерии // Медицина.- 2011.- №11.- C.39-41.
2. Menender R., Martinez R., Reyes S. Biomarkers improve mortality prediction diagnostic scales in community-
acquired pneumonia // Thorax. – 2009. – Vol.64 (7). – P. 587-591.
ANALYSIS OF LEVEL OF BIOMARKERS INFLAMMATION AT COMMUNITY - ACQUIRED PNEUMONIA IN CHILDREN
Karaganda state medical university, Karaganda
The authors concluded that the substantial increase of concentration factor of necrosis of tumor induced depends on
expression of activity of inflammatory process, and with more considerable values in urine. The obtained data in the serum of
blood and urine of children with community acquired pneumonia shows that they play an important role in the mechanisms of
pathogenesis of pneumonias in children and examine the values of necrosis factor of tumor in the serum of blood and urine, as a
laboratory marker of degree of activity of inflammatory process, and accordingly use determination of tactics of curative events for
community- acquired pneumonias in children.
Key words: biomarkers, community-acquired pneumonia, children, inflammatory process
8
Специальный выпуск журнала «Медицина и экология», 2015
МЕДИЦИНСКОЕ ОБРАЗОВАНИЕ — НОВЫЕ ГОРИЗОНТЫ
UTC 618.213
I. V. Bacheva, N. S. Umbetalina, L. G. Turgunova, V. V. Li, A. Z. Fayzullaeva
EFFECT OF MEDICAL AND SOCIAL FACTORS ON THE PREGNANT WOMEN`S
LIFE QUALITY
Karaganda State Medical University, Karaganda
The health of future generations largely determined by the health of the parents, especially mothers,
pregnancy and childbirth. According to experts of the WHO, health is the first criterion of quality of life (QOL) of the
population [cit. 1, 2]. Assessment of pregnant women`s QOL is a promising medicine direction that assess the health
of women not only in the medical aspects, but also in the interrelationship of the woman`s health indicators and
her perception of reality [3].
The aim of the study: to determine effect of medical and social factors on the quality of life of pregnant
women.
The object of the study were 63 pregnant women with pyelonephritis (PP). As a control group were taken 50
practically healthy pregnant women (PH). The control group was individually selected, respectively for each case in
the observation group on the duration of gestation. We worked out a questionnaire indicating medico-social factors
(age, residence, marital status, education, occupation, comorbidities, pernicious habits, etc.) (Table 1). To assess
the degree of medico-social factors effect on pregnant women`s QOL, correlation analysis was conducted, where
the meaning of the correlation coefficient less than 0.3 was assessed as weak connection, if the meaning was from
0.3 to 0.7 - communication was considered to be of medium strength, a meaning from 0.7 to 1.0 was estimated as
close one.
The “+” sign indicates a direct link, while the sign “ - “ on the reverse. To conduct the correlation analysis were
used the following medico-social characteristics of pregnant women: occupation, family relations, relationships with
colleagues, separation from social life, financial stability, commitment to the role of mother, a stressful condition, the
general condition at the time of the survey. (Table 1).
Table 1. The correlation coefficients representing the link of QOL and medico-social characteristics of pregnant
women
Medical and social
factors
Physical working
capacity
Psychological health
General condition
PP
PH
PP
PH
PP
PH
Occupation
0,7
0,6
0,4
0,4
-0,08
-0,06
Financial stability
0,67
0,6
-0,2
-0,3
0,5
0,2
General condition at
the time of the survey
0,8
0,5
0,8
0,6
0,7
0,2
Commitment to the
role of mother
0,7
0,8
-0,7
-0,7
0,00023
0,00023
Family relations
0,1
0,1
0,7
0,53
0,18
0,2
Separation from social
life
-0,76
-0,62
0,4
0,2
-0,3
-0,1
Stressful condition
-0,6
-0,8
0,4
0,2
0,47
0,53
Relationships with
colleagues
-0,04
-0,04
-0,1
-0,1
0,7
0,4
As it is shown by correlation analysis “physical
working capacity
” in both groups has a reliable direct connec-
tion with such medical and social risk factors such as: occupation, financial stability, the general condition at the time
of the survey, commitment to the role of mother, family relations, and inverse reliable link with separation from social
life, stressful condition, relationships with colleagues. (Picture 1). As it can be seen from picture 1, physical
working
capacity
has the highest correlation with the health of pregnant women and the impact on family relationships.
It can be explained by complications of pregnancy such as a deterioration of the general condition of women,
also during pregnancy there is an increase of women weight, circulating blood volume, there is an additional circle
of blood circulation, which leads to lower physical
working capacity
.
“Psychological health” in both groups has a reliable direct connection with such medical and social risk factors
such as: occupation, stress, family relationships, separation from public life, the general condition at the time of
the survey, and inverse reliable link with relationship with colleagues, financial stability, commitment to the role
of mother (Picture 2). From picture 2 it is evident that mental health has the highest correlation with the stress of
Специальный выпуск журнала «Медицина и экология», 2015
9
МЕДИЦИНСКОЕ ОБРАЗОВАНИЕ — НОВЫЕ ГОРИЗОНТЫ
pregnant women and the impact on family relationships, that suggests the stress of women is continued throughout
the pregnancy. The reasons for that is physiological changes in the body, thoughts about upcoming worries about
their health and the health of a child, fear of childbirth.
Picture 2. Correlation analysis depending on the psychological health of the pregnant
Experiences can be associated with information about pregnancy, visits of
maternity welfare center
,
communication with medical staff, conflicts in the family and at work.
“General condition” in both groups has a reliable direct connection with such medical and social risk factors
such as: the relation with colleagues, financial stability, stress, condition at the time of the survey, family relationships,
and inverse reliable link with separation from public life, occupation (Picture 3). As it can be seen from picture 3, the
general condition of the pregnant women has a link with the greatest number of medical and social factors. Very
often pregnant woman is oppressed by stress and anxiety: family discord; material failure; problems on the job and
fear for career; fear of the possible pain in childbirth; all possible experiences related with change in appearance.
Picture 1. Correlation analysis depending on the physical
working capacity
of the pregnant
10
Специальный выпуск журнала «Медицина и экология», 2015
МЕДИЦИНСКОЕ ОБРАЗОВАНИЕ — НОВЫЕ ГОРИЗОНТЫ
States before pregnancy were quite common, but in pregnancy same conditions are felt too emotional, that
has an impact on the decrease in QOL.
Picture 3. Correlation analysis depending on the general condition of the pregnant
Thus, the results of the study showed that pregnant women with pyelonephritis who were compared with
healthy pregnant women has closer correlation with such medical and social factors such as family relationships,
financial stability, commitment to the role of mother, stressful condition, general condition at the time of the survey,
probably due to the influence of the disease itself.
References
1. Черепов Е.М. Проблемы улучшения качества жизни населения / Е.М. Черепов // Гигиена и санитария. -
2001. - № 5. - С. 39-41.
2. Петров В.И. Базисные принципы и методология доказательной медицины / В.И. Петров // Вестник
Волгоградского государственного медицинского университета. – 2011. – Т. 38. - №2. – С. 3–9.
3. Говоров С.В. Сравнительная оценка компонентов качества жизни беременных и родильниц / С.В. Говоров,
Г.Я. Клименко // Уральский медицинский журнал. – 2008. – № 1(41). – С. 99-102.
I. V. Bacheva, N. S. Umbetalina, L. G. Turgunova, V. V. Li, A. Z. Fayzullaeva
EFFECT OF MEDICAL AND SOCIAL FACTORS ON THE PREGNANT WOMEN`S LIFE QUALITY
Karaganda State Medical University, Karaganda
The authors made the conclusion, that the results of the study showed that pregnant women with pyelonephritis who were
compared with healthy pregnant women has closer correlation with such medical and social factors such as family relationships,
financial stability, commitment to the role of mother, stressful condition, general condition at the time of the survey, probably due
to the influence of the disease itself.
Key words: medicine, social factors, life quality, pregnancy, pyelonephritis
Специальный выпуск журнала «Медицина и экология», 2015
11
МЕДИЦИНСКОЕ ОБРАЗОВАНИЕ — НОВЫЕ ГОРИЗОНТЫ
УДК 61(07)
P. Bamidis, D. Spachos, E. Konstantinidis, P. Antoniou
EDUCATIONAL TECHNOLOGIES LIVING LAB: IT’S ROLE IN HEALTHCARE EDUCATION AND
REQUIRED INFRASTRUCTURES
Faculty of Health Sciences, Aristotle University of Thessaloniki
Over the last year, our research team at the Medical School of the Aristotle University of Thessaloniki (AUTH)
has made efforts to establish an ecologically valid educational technology living lab within the lab of Medical Physics.
This consists of a living-room like space. Students and educators visit the Living Lab and may perform educational
interactions for 1-3 hours. They can also relax and perform different daily activities; users are also asked to utilize a
smart watch; a Smart TV and a PC with an Android Box and a kinect are also available for any web or other app use;
a Tablet with different apps is also available different health measurement devices (blood pressure monitor; wireless
EEG, skin conductance, etc) are also available for on-demand measurements. Finally, a fisheye camera on the ceiling
may monitor the participants movements.
The Living Lab Monitoring services and software include: a) Emotion Registration App (subjectively done
through a simple interface; stats are recorded for the educator); b) Cognitive and neurofeedback training for up-scal-
ing performance (score based); c) Annotation tool utilized by an observer during any educational interaction session;
d) Data fusion algorithms (based on fuzzy cognitive maps and/or trend analysis); e) iSPy for recording IP cameras;
f) Audacity software for recording raw audio data; g) CAC-framework for recording RGB and skeleton from Kinect as
well as Center of mass from Wii Balance Boards.
In this presentation, we demonstrate the role this Living Lab may play in reforming medical (and healthcare)
education with specific use case examples. Extending and fusing the Lab’s infrastructure with that of the Affective
and Applied Neuroscience Research Group, give rise to exciting new prospects for the domain of Educational Neuro-
science and its application in healthcare education.
UTC 61(07)
P. Bamidis, M. Nikolaidou, E. Dafli
WEB TECHNOLOGIES IN HEALTHCARE EDUCATION: A TEN YEAR RECORD TRACK IN FUND-
ED RESEARCH & PRACTICE
Faculty of Health Sciences, Aristotle University of Thessaloniki
Over the last decade, our research team at the Medical School of the Aristotle University of Thessaloniki
(AUTH) has made several efforts to improve medical education by assimilating new technological and pedagogical
trends. So, the Medical Education Informatics Research Group (MEI, http://medphys.med.auth.gr/group/mei) has
been focusing on exploring shifting paradigms in education and breakthroughs in information technologies for
implementation in novel and impactful learning modalities in healthcare education.
Axis 1: emphasis is drawn on exploring contemporary pedagogies in medical (and dental) education focusing
on experiential and active learning (problem based learning, case/scenario-based learning, virtual patients, serious
games etc) in an effort of providing medical students and healthcare learners with rich interactive educational
content in order to facilitate their need for rapid absorption of the ever evolving healthcare curriculum and with the
long term goal being the modernisation of the curriculum.
Axis 2: focus here is on innovations in remote healthcare education, through technologies that facilitate
continuing training for healthcare professionals by bringing the expert close to the learner and keeping the level
of healthcare expertise consistent irrespectively of the professional’s distance from large educational or healthcare
institutions (Universities, Hospitals). Training of care givers for special target groups like the elderly, the disabled and
the chronic patients, has also been tackled.
Axis 3: extensive research in information communication technologies (ICTs), especially e-learning standards
and semantic technologies, aims to facilitate the aggregation, repurposing and reusability of the ever expanding
healthcare educational content. The central theme here has always been the consolidation of healthcare education
resources, their discoverability and availability to the widest part of its consumers, be them learners/students or
educators/teachers, and the openness in healthcare education.
So in this presentation we revisit the considerable involvement of our group in funded national and interna-
tional projects over the past decade with specific examples of the aforementioned research endeavors in all the above
fields. The presentation will conclude with how this makes a unique ingredient list for a successful continuation and
sustainability of the ePBLnet (
www.epblnet.eu
) beyond its project timeline.
12
Специальный выпуск журнала «Медицина и экология», 2015
МЕДИЦИНСКОЕ ОБРАЗОВАНИЕ — НОВЫЕ ГОРИЗОНТЫ
УTC 616.322-002/.321-002-085
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